Vile (2011)

McKenzie Westmore, Ian Bohen, Rob Kirkland, Greg Cipes

A group of friends stop to pick up a hitchhiking woman only to end up getting drugged by her with a gas. They awaken to find that vials have been implanted in the base of their skulls - which are of course instantly fatal if they are removed, a grinning professional looking woman informs them on TV